Ibuprofen may increase risk of fertility issues in men, study suggests
Men who take high doses of ibuprofen for months at a time may be at greater risk of fertility issues and also other health problems, such as muscle wastage, erectile dysfunction and fatigue, scientists have found.
Research on healthy young men who took the common painkiller for up to six weeks showed that the drug disrupted the production of male sex hormones and led to a condition normally seen in older men and smokers.
The 18 to 35-year-olds who took part in the study developed a disorder called “compensated hypogonadism” within two weeks of having 600mg of ibuprofen twice a day. The condition arises when the body has to boost levels of testosterone because normal production in the testes has fallen.
Doctors in Copenhagen who led the study said that while the disorder was mild and temporary in the volunteers, they feared it could become permanent in long-term ibuprofen users. This would lead to continuously low levels of testosterone, because the body could no longer compensate for the fall.
“Our immediate concern is for the fertility of men who use these drugs for a long time,” said David Møbjerg Kristensen at the University of Copenhagen. “These compounds are good painkillers, but a certain amount of people in society use them without thinking of them as proper medicines.”
Bernard Jégou, a senior author on the study at the French National Institute of Health and Medical Research, said he saw no problem in people taking ibuprofen to alleviate pain in the short term – for toothache, for example – but warned against taking the drug for months on end if it was not strictly necessary.
“We normally see this condition in elderly men, so it raises an alarm,” Jégou said. “We are concerned about it, particularly for healthy people who don’t need to take these drugs. The risk is greater than the benefit.”
The finding comes after repeated warnings from other researchers that ibuprofen can raise the risk of heart attacks in the general population and cause medical problems for pregnant women and their babies, including a more than doubling of the risk of miscarriage.
In the latest research, scientists looked at the impact of ibuprofen on 31 healthy young men over six weeks and performed further tests on cells and pieces of human testes in the lab.
https://www.theguardian.com/science/201 ... y-suggests
Ibuprofen Studie (Fruchtbarkeit bei Männern)
1heute zufällig gelesen. Dachte ich gebs mal weiter (gibt es leider nicht auf deutsch):
Die Peitsche tut schon weh.
